Top 10 Most Important Organic Reactions for NEET 2025

Top 10 Most Important Organic Reactions for NEET 2025

Organic Chemistry is one of the most scoring yet tricky parts of NEET. If you know the key reactions, reagents, and mechanisms, you can easily solve 8–10 questions in the NEET exam. Here we present the Top 10 must-know organic reactions for NEET 2025 preparation.

🔬 Top 10 Organic Reactions for NEET:

1. Aldol Condensation
   Reactant: Aldehyde with α-hydrogen
   Reagent: Dilute NaOH
   Product: β-hydroxy aldehyde → α,β-unsaturated aldehyde
2. Cannizzaro Reaction
   Reactant: Aldehydes with no α-hydrogen
   Reagent: Concentrated NaOH
   Product: Alcohol + Salt of carboxylic acid
3. Sandmeyer Reaction
   Converts diazonium salt to aryl halides
   Reagents: CuCl / CuBr / CuCN
4. Wurtz Reaction
   Alkyl halide + Na → Alkane
   Only works well with symmetric alkanes
5. Friedel–Crafts Alkylation/Acylation
   Reagent: AlCl₃
   Aromatic substitution reaction
6. Kolbe’s Reaction
   Phenol + CO₂ → Salicylic Acid
   Industrial use in aspirin synthesis
7. Hell-Volhard-Zelinsky Reaction (HVZ)
   Converts carboxylic acids to α-halo acids
   Reagents: Cl₂ + Red P
8. Reimer–Tiemann Reaction
   Phenol + CHCl₃ + NaOH → Salicylaldehyde
9. Gabriel Phthalimide Synthesis
   Primary amine formation from phthalimide + alkyl halide
10. Hydroboration-Oxidation
    Converts alkene → Alcohol
    Reagents: BH₃-THF + H₂O₂/OH⁻